| Date | Location | Result | |
| Nov 20, 2010 | Edwardsville, Pa. | Moravian College 26, Wilkes University 14 | Box score |
| Nov 13, 2010 | Edwardsville, Pa. | Wilkes University 21, King's College 17 | Box score |
| 11/06/10 | Chester, PA | Widener 41, Wilkes University 21 | Box score |
| Oct 30, 2010 | Edwardsville, Pa. | Wilkes University 31, Lycoming College 14 | Box score |
| Oct 23, 2010 | Madison, NJ | Wilkes University 28, FDU-Florham 23 | Box score |
| Oct 16, 2010 | Edwardsville, Pa. | Delaware Valley 30, Wilkes University 18 | Box score |
| Oct 09, 2010 | Annville, Pa. | Wilkes University 35, Lebanon Valley 28 | Box score |
| Oct 02, 2010 | Edwardsville, Pa. | Wilkes University 38, ALBRIGHT 35 | Box score |
| Sep 25, 2010 | Utica, N.Y. | Utica College 24, Wilkes University 10 | Box score |
| Sep 17, 2010 | Edwardsville, Pa. | Springfield 44, Wilkes University 7 | Box score |
| Sep 11, 2010 | Edwardsville, PA | Wilkes University 38, Waynesburg 35 | Box score |