| Date | Location | Result | |
| Oct 30, 2010 | Edwardsville, Pa. | Misericordia 2, Wilkes University 1 | Box score |
| Oct 26, 2010 | Edwardsville, Pa. | SUNY Cortland 1, Wilkes University 0 | Box score |
| Oct 23, 2010 | Edwardsville, Pa. | Manhattanville 2, Wilkes University 1 | Box score |
| Oct 19, 2010 | Wilkes-Barre, Pa. | Wilkes University 0, King's College 0 | Box score |
| Oct 16, 2010 | Madison, NJ | Wilkes University 0, FDU-Florham 0 | Box score |
| Oct 13, 2010 | Edwardsville, Pa. | Wilkes University 1, DeSales 0 | Box score |
| Oct 09, 2010 | St. Davids, Pa. | Eastern University 4, Wilkes University 2 | Box score |
| Oct 05, 2010 | Edwardsville, Pa. | Elizabethtown 4, Wilkes University 1 | Box score |
| Oct 02, 2010 | Edwardsville, Pa. | Wilkes University 2, Delaware Valley 0 | Box score |
| Sep 29, 2010 | Edwardsville, Pa. | Wilkes University 3, Susquehanna 1 | Box score |
| 09/24/10 | Riverdale, NY | NYU 1, Wilkes University 0 | Box score |
| Sep 21, 2010 | Hackettstown, N.J. | Centenary Cyclones 1, Wilkes University 0 | Box score |
| 9/17/10 | Chester, PA | Widener 1, Wilkes University 0 | Box score |
| Sep 16, 2010 | Annville, Pa. | Wilkes University 3, Lebanon Valley 1 | Box score |
| Sep 11, 2010 | Edwardsville, Pa. | Wilkes University 1, Moravian 0 | Box score |
| 9-8-10 | Scranton, Pa. | Scranton 1, Wilkes University 0 | Box score |
| Sep 05, 2010 | Pomona, NJ | Rowan 5, Wilkes University 0 | Box score |
| Sep 04, 2010 | Pomona, NJ | Richard Stockton 2, Wilkes University 1 | Box score |
| Sep 01, 2010 | Edwardsville, PA | Wilkes University 1, Marywood 0 | Box score |